José Bayoán Santiago Calderón

José Bayoán Santiago Calderón

(he/him)

Senior Research Economist

U.S. Bureau of Economic Analysis

Professional Summary

Dr. Santiago Calderón is a senior research economist in the national economic accounts research group at the U.S. Bureau of Economic Analysis. Before joining the federal statistical system, he had years of experience in the private sector as a research scientist at various companies. Bayoán also held academic appointments with the Biocomplexity Institute and Initiative at the University of Virginia, where he started his career in public service.

His research has centered on improving decision-making. His transdisciplinary research approach has enabled him to routinely collaborate across disciplines and develop a diverse set of domain knowledge and methodological toolset. He also participates in various open-source software communities (e.g., JuliaLang) and civic activism (e.g., Code4PR, Mentes Puertorriqueñas en Accion).

Research and public impact

My work sits at the intersection of economics, public policy, and computational methods. I have developed research around official statistics, digital economy measurement, and the use of data-intensive methods to inform evidence-based decisions.

I am especially interested in building reproducible analyses and open-source tools that make complex questions more transparent and actionable.

Experience

U.S. Bureau of Economic Analysis logo

Senior Research Economist · Full-time

U.S. Bureau of Economic Analysis

- Published research on national economic accounts and measurement issues, primarily focusing on intellectual property products (IPPs), such as software and data assets.

- Contributed to official statistics through innovative methodologies and operational enhancements. Some examples include the use of big data, natural language processing (NLP), and machine learning, implemented in Python, R, Julia, MATLAB, and Stata.

- Collaborated and engaged with stakeholders, including members of international expert groups and policymakers.Research on digital economy measurement, intellectual property products, own-account software, and data assets in national accounts.

Pumas-AI logo

Senior Scientist II · Contract · Part-time

Pumas-AI

Provided strategic and scientific consulting services in model-informed drug development (MIDD), including exposure-response analysis and clinical trial simulations across multiple therapeutic areas, such as rare diseases, metabolic diseases, oncology, and vaccines. Some of the technologies used for the work include Pumas, Julia, R, and SAS. Strategic and scientific consulting for clinical development and product development, including bioequivalence workflows and quantitative software tooling.
University of Virginia logo

Postdoctoral Research Associate · Full-time

University of Virginia

- Provided government clients consulting services in the areas of science policy, labor economics, computational models, and program evaluation through problem identification, data discovery (inventory, screening, acquisition), data ingestion, data wrangling (profiling, preparation, linkage, and exploration), fitness-for-use assessment, statistical modeling, and analysis.

- The work employed high-performance computing (HPC) environment and tools like Slurm, Git, containers, and databases (PostgreSQL) to store and access billions of records, some collected through APIs (e.g., REST, GraphQL) that were used in natural language processing (NLP), geographic information systems (GIS), agent-based modeling (ABM), graph theory, and regression analysis using SQL, Julia, and R.

- Led and supported interdisciplinary public-sector analytics projects, including open-source software measurement, workforce studies, and public safety evaluation.

JuliaHub logo

Consultant · Contract

JuliaHub

Developed components for integrated scientific modeling, simulation, and AI/ML software for quantitative work required by regulatory agencies throughout the drug development cycle. My primary contribution was the development of the bioequivalence module, used in successful FDA submissions.
QuantEcon logo

Research Assistant · Contract

QuantEcon

Contributed to QuantEcon lecture development and Julia ecosystem modernization.
Virginia Tech logo

Data Science for the Public Good Fellow · Contract

Virginia Tech

Worked on public-interest projects spanning open-source software measurement and program evaluation.
Res-Intel logo

Data Scientist · Contract

Res-Intel

- Developed the statistical components for the mass-scale residential building energy benchmarking used in demand side management (DSM). The work leveraged various data sources, including real estate information, government administrative records (e.g., building footprint, zoning), weather records, geographic information systems (GIS) layers, and utility meter data. Some of the technologies employed include APIs, databases (SQL), and R.

- Delivered commissioned reports and analyses related to program evaluations of building policies and energy use programs in California.

Michigan State University logo

Research Fellow · Contract

Michigan State University

Teaching assistant for the advanced research course at the American Economic Association (AEA) Summer Program taught by Dr. Lisa D. Cook.
Johns Hopkins University logo

Teaching Assistant · Contract

Johns Hopkins University

Supported fundamentals of microeconomics instruction in the CTY program.
Center for Neuroeconomics Studies logo

Research Assistant · Part-time

Center for Neuroeconomics Studies

- Conducted neuroeconomic studies, encompassing aspects of study design, recruitment, experimentation, and data analysis, included in published academic articles.

- Collected and analyzed biometric data, including EDA/GSR, EEG, ECG, and eyetracking, using iMotions.

Sapientis logo

Intern · Contract · Full-time

Sapientis

Supported education-policy research and reporting through the PARACa fellowship program.

Education

Claremont Graduate University logo
Claremont Graduate University logo
Southwestern University logo
Minors in Mathematics, Political Science, French, and Chinese. Semesters abroad in Shanghai and Paris.
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Conferences and Talks